Altered Expression Ratio of Actin-Binding Gelsolin Isoforms Is a Novel Hallmark of Mitochondrial OXPHOS Dysfunction

Mitochondrial oxidative phosphorylation (OXPHOS) defects are the primary cause of inborn errors of energy metabolism.Despite considerable Soft shell progress on their genetic basis, their global pathophysiological consequences remain undefined.Previous studies reported that OXPHOS dysfunction associated with complex III deficiency exacerbated the e

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Decision-Making Within Forensic Psychiatric Investigations: The Use of Various Information Sources by Different Expert Groups to Reach Conclusions on Legal Insanity

BackgroundWhich type of information experts use to make decisions regarding legal insanity within forensic psychiatric investigations (FPI) is relatively unknown, both in general and when considering variations due to case context.It is important to explore this area to be able to counteract the effects of various kinds of cognitive bias.MethodThe

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Fatores associados à participação em programas comunitários de atividade física: Pesquisa Nacional de Saúde 2019

Apesar dos investimentos realizados ao redor do mundo, seja no âmbito acadêmico, seja na implementação de políticas públicas, os níveis de atividade física não têm aumentado a contento.Assim, o objetivo deste trabalho é identificar quais os fatores que influenciam na participação em Programas Comunitários de Atividade Física na reali

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